Implementing Rapid Whole-Genome Sequencing in Critical Care: A Qualitative Study of Facilitators and Barriers to New Technology Adoption.
J Pediatr
; 237: 237-243.e2, 2021 10.
Article
em En
| MEDLINE
| ID: mdl-34023348
ABSTRACT
OBJECTIVE:
To characterize the views of members of the multi-disciplinary team regarding the implementation of rapid whole-genome sequencing (rWGS) as a first-tier test for critically ill children in diverse children's hospital settings. STUDYDESIGN:
Qualitative interviews informed by implementation science theory were conducted with the multidisciplinary patient care teams and hospital leaders at each of the 5 tertiary care children's hospitals involved in a statewide rWGS implementation project.RESULTS:
Our analysis revealed 5 key themes regarding the implementation process across the sites the need for rWGS champions, educational needs and strategies, negotiating decision-making roles and processes, workflows and workarounds, and perceptions about rWGS. From the findings a composite clinical workflow diagram was developed to summarize all of the processes involved in the implementation of the test, and the key areas where implementation practices differed.CONCLUSIONS:
These findings provide insights for design of interventions to support adoption, scale-up, and sustainability of rWGS and other novel technologies in neonatal and pediatric critical care settings.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cuidados Críticos
/
Doenças Raras
Tipo de estudo:
Prognostic_studies
/
Qualitative_research
Limite:
Child
/
Humans
/
Newborn
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article