Relationship between carbohydrate intake and oral glucose tolerance test results among pregnant women.
Diabetes Res Clin Pract
; 176: 108869, 2021 Jun.
Article
em En
| MEDLINE
| ID: mdl-34029622
ABSTRACT
AIMS:
Evaluate the relationship between self-reported carbohydrate intake and oral glucose tolerance test (OGTT) results in pregnancy.METHODS:
We measured carbohydrate intake using 24-hour dietary recall and performed a 2-hour 75-gram OGTT in 95 pregnant women with risk factors for gestational diabetes (GDM) at a median of 26 weeks' gestation. We tested for associations between carbohydrate intake in the 24 hours preceding the OGTT and 60-minute OGTT glucose, glucose at other timepoints, and glucose area under the curve (AUC) using linear regression, with adjustment for potential confounders.RESULTS:
We observed an inverse linear relationship between carbohydrate intake (median 237 grams [interquartile range 196, 303]) and 60-minute OGTT glucose. For every 50 gram reduction in carbohydrate intake, there was an 8.9 mg/dl increase in 60-minute OGTT glucose (P < 0.01) in an adjusted model. Lower carbohydrate intake was also associated with higher 30-minute (adjusted ß = -6.5 mg/dl, P < 0.01) and 120-minute OGTT glucose (adjusted ß = -8.1 mg/dl, P = 0.01) and AUC (adjusted ß = -767, P < 0.01).CONCLUSIONS:
Carbohydrate intake in the day preceding an OGTT in pregnancy is associated with post-load glucose values, with lower carbohydrate intake predicting higher glucose levels and higher carbohydrate intake predicting lower glucose levels. Carbohydrate restriction or excess before an OGTT may affect GDM diagnosis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gravidez
/
Carboidratos da Dieta
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Fenômenos Fisiológicos da Nutrição Materna
/
Glucose
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article