[Detection of the binding of 131I-meta-iodobenzylguanidine to structures of the plasma membranes of neuroblastoma cell lines]. / Nachweis der Bindung von 131J-Meta-Jod-Benzylguanidin an Strukturen der Plasmamembran von Neuroblastom-Zellinien.
Nuklearmedizin
; 27(3): 95-7, 1988 Jun.
Article
em De
| MEDLINE
| ID: mdl-3405781
ABSTRACT
In vitro studies of tumor tissue have shown that 131I-IBG is specifically bound to the plasma membrane-enriched fraction of two neuroblastoma cell lines (NA-2 and C-1300). NB C-1300 showed a slightly higher binding capacity than NB NA-2. It may be inferred from experiments performed with activators of the adrenergic and dopaminergic systems that binding of IBG to proteins on the plasma membrane which is physiologically important for binding of this guanidine derivative, is probable.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Membrana Celular
/
Radioisótopos do Iodo
/
Iodobenzenos
/
Neuroblastoma
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Humans
Idioma:
De
Ano de publicação:
1988
Tipo de documento:
Article