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Prevalence of latent tuberculosis in patients with hematological neoplasms in a cancer referral hospital in Mexico City.
Osorio-López, Erick Antonio; Vilar-Compte, Diana; García-Tirado, Jaquelyn; Martin-Onraet, Alexandra.
Afiliação
  • Osorio-López EA; Faculty of Medicine, National Autonomous University of Mexico (Universidad Nacional Autonoma de México), Mexico City, Mexico.
  • Vilar-Compte D; Department of Infectious Diseases, National Cancer Institute (Instituto Nacional de Cancerologia), Av. San Fernando 22, col. Sección XVI. 14000, Tlalpan Delegation, Mexico City, Mexico.
  • García-Tirado J; Department of Infectious Diseases, National Cancer Institute (Instituto Nacional de Cancerologia), Av. San Fernando 22, col. Sección XVI. 14000, Tlalpan Delegation, Mexico City, Mexico.
  • Martin-Onraet A; Faculty of Medicine, National Autonomous University of Mexico (Universidad Nacional Autonoma de México), Mexico City, Mexico.
BMC Infect Dis ; 21(1): 510, 2021 May 31.
Article em En | MEDLINE | ID: mdl-34059022
OBJECTIVE: To determine the prevalence of Latent Tuberculosis in patients with hematological neoplasms at the Instituto Nacional de Cancerología in Mexico City using the Tuberculin skin test (TST). METHODS: This retrospective study included all patients with a recent diagnosis of hematological neoplasms who were admitted for treatment from 2017 to 2018 and who were screened for latent tuberculosis with the TST. The prevalence of latent tuberculosis in this group, tolerance and therapeutic adherence in treated patients are described. RESULTS: The files of 446 patients with hematological malignancy who had a TST were reviewed. The prevalence of latent tuberculosis was 31.2% (n = 139). Ninety-three patients received isoniazid, 15.1% had some adverse reactions, but only 4 (4.3%) had to discontinue treatment. Two patients with latent tuberculosis under treatment with Isoniazid reactivated tuberculosis infection. CONCLUSIONS: The prevalence in our study was within the range of other similar Mexican populations. Isoniazid treatment had an adequate tolerance and adherence. Longer follow-up could offer more information on the risk of reactivation in both groups.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Hematológicas / Tuberculose Latente Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Hematológicas / Tuberculose Latente Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Ano de publicação: 2021 Tipo de documento: Article