A Kidney Transplant Recipient With a Perforated Cheek: Oral Epstein-Barr Virus-Positive Mucocutaneous Ulcer Complicated With an Opportunistic Bacterial Infection.
Exp Clin Transplant
; 19(8): 868-870, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-34085910
ABSTRACT
A 69-year-old female living donor kidney transplant recipient presented with right facial painful edema. The patient's body mass index was 14 (kilograms per meter squared), and her creatinine clearance was 15 mL/min. A computed tomography detected a subcutaneous mass under the nasolabial fold in contact with the maxillary bone. A biopsy from an ipsilateral oral mucosal ulcer returned the diagnosis of Epstein-Barr virus-positive mucocutaneous ulcer. Within 2 weeks, the lesion perforated the tissue. The mass and the affected bone were removed, and histopathology detected inflammation with many microorganisms. The opportunistic pathogen Streptococcus anginosus was isolated from wound cultures. Immunosuppressives were restricted, antibiotics were administered, and the patient started hemodialysis. Rituximab was applied for the lymphoproliferative disease. The lesion healed, allowing for surgical restoration. Two years later, the patient has remained free of local pathology and with improved nutritional and functional status. Epstein-Barr virus-positive muco cutaneous ulcers should be considered in the differential diagnosis of oral and facial lesions of immunocompromised patients and may be complicated with bacterial infections.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Oportunistas
/
Transplante de Rim
/
Úlceras Orais
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Infecções por Vírus Epstein-Barr
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Gastroenteropatias
/
Transtornos Linfoproliferativos
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Aged
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Female
/
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article