Clinical Outcome in Children with Chemotherapy-Induced Mucositis.
Semin Oncol Nurs
; 37(3): 151160, 2021 06.
Article
em En
| MEDLINE
| ID: mdl-34088558
ABSTRACT
OBJECTIVES:
This study was conducted to assess the impact of oral mucositis on nutrition and performance status in pediatric cancer patients treated by chemotherapy. DATA SOURCES A total of 46 children were followed for mucositis episode, and their mean Oral Assessment Guide score was 20.2. Main concomitant disorders were hematological changes (86.9%), loss of appetite (60.7%), vomiting (28.3%), and diarrhea (10.9%).CONCLUSION:
Anthropometric changes were highlighted by a decrease in body mass index (Pâ¯=â¯.03) and a decrease of Waterlow score (Pâ¯=â¯.007). Most patients had a low Lansky Play Performance Scale (LPPS) ≤40 (86.9%). High mucositis grades (Pâ¯=â¯.007) and long hospital stay (Pâ¯=â¯.005) were associated with a significant reduction in Lansky Play Performance Scale. Patient's follow-up showed need for hospitalization (84.8%), delay in chemotherapy treatment (71.7%), use of opioides (34.8%), and use of parenteral nutrition (26.1%). Death occurred in 10.9% of the cases. IMPLICATIONS FOR NURSING PRACTICE These findings illustrate the impact of mucositis on nutrition and performance status in children undergoing chemotherapy, which considerable affected their outcome.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estomatite
/
Mucosite
/
Neoplasias
/
Antineoplásicos
Limite:
Child
/
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article