HIV-1 sequences in lentiviral vector genomes can be substantially reduced without compromising transduction efficiency.

Sertkaya, Helin; Ficarelli, Mattia; Sweeney, Nathan P; Parker, Hannah; Vink, Conrad A; Swanson, Chad M

Sertkaya, Helin; Ficarelli, Mattia; Sweeney, Nathan P; Parker, Hannah; Vink, Conrad A; Swanson, Chad M.

Afiliação

Sertkaya H; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK.
Ficarelli M; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK.
Sweeney NP; Cell & Gene Therapy Platform, Medicinal Science and Technology, GSK, Stevenage, SG1 2NY, UK.
Parker H; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK.
Vink CA; Cell & Gene Therapy Platform, Medicinal Science and Technology, GSK, Stevenage, SG1 2NY, UK. conrad.x.vink@gsk.com.
Swanson CM; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK. chad.swanson@kcl.ac.uk.

Sci Rep ; 11(1): 12067, 2021 06 08.

Article em En | MEDLINE | ID: mdl-34103612

Assuntos

Vetores Genéticos/genética; Genoma Viral; HIV-1/genética; Transdução Genética; Células HEK293; Humanos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução Genética / HIV-1 / Genoma Viral / Vetores Genéticos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google