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Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights.
Abdelgawad, Mohamed A; Musa, Arafa; Almalki, Atiah H; Alzarea, Sami I; Mostafa, Ehab M; Hegazy, Mostafa M; Mostafa-Hedeab, Gomaa; Ghoneim, Mohammed M; Parambi, Della G T; Bakr, Rania B; Al-Muaikel, Nayef S; Alanazi, Abdullah S; Alharbi, Metab; Ahmad, Waqas; Bukhari, Syed N A; Al-Sanea, Mohammad M.
Afiliação
  • Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia.
  • Musa A; Department of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, 72341, Saudi Arabia.
  • Almalki AH; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, 21944, Saudi Arabia.
  • Alzarea SI; Addiction and Neuroscience Research Unit, Taif University, Taif, 21944, Saudi Arabia.
  • Mostafa EM; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia.
  • Hegazy MM; Department of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, 72341, Saudi Arabia.
  • Mostafa-Hedeab G; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, 11371, Egypt.
  • Ghoneim MM; Department of Pharmacology, Medical College, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia.
  • Parambi DGT; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, 11371, Egypt.
  • Bakr RB; Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Ad Diriyah, 13713, Saudi Arabia.
  • Al-Muaikel NS; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia.
  • Alanazi AS; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia.
  • Alharbi M; Department of Chemistry, College of Science, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia.
  • Ahmad W; Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
  • Bukhari SNA; Health Sciences Research Unit, Jouf University, Sakaka, Aljouf, Saudi Arabia.
  • Al-Sanea MM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Drug Des Devel Ther ; 15: 2325-2337, 2021.
Article em En | MEDLINE | ID: mdl-34103896
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Extratos Vegetais / Desenho de Fármacos / Inibidores de Proteínas Quinases / Inibidores de Ciclo-Oxigenase 2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Extratos Vegetais / Desenho de Fármacos / Inibidores de Proteínas Quinases / Inibidores de Ciclo-Oxigenase 2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article