Low-Molecular-Weight Poly(ethylenimine) Nanogels Loaded with Ultrasmall Iron Oxide Nanoparticles for <i>T</i><sub>1</sub>-Weighted MR Imaging-Guided Gene Therapy of Sarcoma.

Peng, Yucheng; Gao, Yue; Yang, Chao; Guo, Rui; Shi, Xiangyang; Cao, Xueyan

Low-Molecular-Weight Poly(ethylenimine) Nanogels Loaded with Ultrasmall Iron Oxide Nanoparticles for T₁-Weighted MR Imaging-Guided Gene Therapy of Sarcoma.

Peng, Yucheng; Gao, Yue; Yang, Chao; Guo, Rui; Shi, Xiangyang; Cao, Xueyan.

Afiliação

Peng Y; State Key Laboratory for Modification of Chemical Fiber and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Gao Y; State Key Laboratory for Modification of Chemical Fiber and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Yang C; State Key Laboratory for Modification of Chemical Fiber and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Guo R; State Key Laboratory for Modification of Chemical Fiber and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Shi X; State Key Laboratory for Modification of Chemical Fiber and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Cao X; State Key Laboratory for Modification of Chemical Fiber and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.

ACS Appl Mater Interfaces ; 13(24): 27806-27813, 2021 Jun 23.

Article em En | MEDLINE | ID: mdl-34105346

Assuntos

Portadores de Fármacos/química; Nanopartículas de Magnetita/química; Nanogéis/química; Polietilenoimina/química; RNA Interferente Pequeno/uso terapêutico; Sarcoma/terapia; Animais; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Inativação Gênica; Técnicas de Transferência de Genes; Terapia Genética; Imageamento por Ressonância Magnética; Camundongos; Peso Molecular; Fator de Crescimento Transformador beta1/genética

Palavras-chave

MR imaging; PEI; TGF-ß1 siRNA; gene therapy; nanogels

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoimina / Sarcoma / Portadores de Fármacos / RNA Interferente Pequeno / Nanopartículas de Magnetita / Nanogéis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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