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A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy.
Chidiac, Rony; Abedin, Md; Macleod, Graham; Yang, Andy; Thibeault, Pierre E; Blazer, Levi L; Adams, Jarrett J; Zhang, Lingling; Roehrich, Heidi; Jo, Ha-Neul; Seshagiri, Somasekar; Sidhu, Sachdev S; Junge, Harald J; Angers, Stephane.
Afiliação
  • Chidiac R; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
  • Abedin M; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
  • Macleod G; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
  • Yang A; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
  • Thibeault PE; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
  • Blazer LL; AntlerA Therapeutics, Foster City, CA, USA.
  • Adams JJ; AntlerA Therapeutics, Foster City, CA, USA.
  • Zhang L; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
  • Roehrich H; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
  • Jo HN; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
  • Seshagiri S; AntlerA Therapeutics, Foster City, CA, USA.
  • Sidhu SS; AntlerA Therapeutics, Foster City, CA, USA.
  • Junge HJ; Donnelly Centre, University of Toronto, Toronto, ON, Canada.
  • Angers S; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
EMBO Mol Med ; 13(7): e13977, 2021 07 07.
Article em En | MEDLINE | ID: mdl-34105895

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Células Endoteliais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Células Endoteliais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article