Uterine NK cell education: Learning the ropes in pregnancy.

Wells, Alexandra I; Coyne, Carolyn B

Wells, Alexandra I; Coyne, Carolyn B.

Afiliação

Wells AI; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Coyne CB; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: carolyn.coyne@duke.edu.

Immunity ; 54(6): 1102-1104, 2021 06 08.

Article em En | MEDLINE | ID: mdl-34107267

ABSTRACT

ABSTRACT

The impact of inhibitory receptor NKG2A-mediated education on uterine NK (uNK) cell responsiveness to vascular remodeling on pregnancy outcomes has remained unclear. In this issue of Immunity, Shreeve et al. show that loss of NKG2A+ uNK cells results in deficient vascularization and restricted fetal growth.

Assuntos

Células Matadoras Naturais; Útero; Feminino; Humanos; Neovascularização Patológica; Gravidez; Remodelação Vascular

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Útero / Células Matadoras Naturais Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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