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High-dose Mycobacterium tuberculosis aerosol challenge cannot overcome BCG-induced protection in Chinese origin cynomolgus macaques; implications of natural resistance for vaccine evaluation.
Sibley, Laura; White, Andrew D; Gooch, Karen E; Stevens, Lisa M; Tanner, Rachel; Jacobs, Ashley; Daykin-Pont, Owen; Gleeson, Fergus; McIntyre, Anthony; Basaraba, Randall; Clark, Simon; Hall, Graham; Pearson, Geoff; Rayner, Emma; McShane, Helen; Williams, Ann; Dennis, Mike; Marsh, Philip D; Sharpe, Sally.
Afiliação
  • Sibley L; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK. laura.sibley@phe.gov.uk.
  • White AD; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Gooch KE; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Stevens LM; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Tanner R; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK.
  • Jacobs A; University of Cape Town, Cape Town, South Africa.
  • Daykin-Pont O; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Gleeson F; Churchill Hospital, Headington, Oxford, UK.
  • McIntyre A; Churchill Hospital, Headington, Oxford, UK.
  • Basaraba R; Colorado State University, Fort Collins, CO, USA.
  • Clark S; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Hall G; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Pearson G; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Rayner E; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • McShane H; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK.
  • Williams A; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Dennis M; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Marsh PD; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
  • Sharpe S; National Infection Service, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK.
Sci Rep ; 11(1): 12274, 2021 06 10.
Article em En | MEDLINE | ID: mdl-34112845

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Vacina BCG / Interações Hospedeiro-Patógeno / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Vacina BCG / Interações Hospedeiro-Patógeno / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article