Ochratoxin A induces ERK1/2 phosphorylation-dependent apoptosis through NF-&#954;B/ERK axis in human proximal tubule HK-2 cell line.

Darbuka, Elif; Gürkaslar, Can; Yaman, Ibrahim

Ochratoxin A induces ERK1/2 phosphorylation-dependent apoptosis through NF-κB/ERK axis in human proximal tubule HK-2 cell line.

Darbuka, Elif; Gürkaslar, Can; Yaman, Ibrahim.

Afiliação

Darbuka E; Bogazici University, Department of Molecular Biology and Genetics, Molecular Toxicology and Cancer Research Laboratory, Bebek, Istanbul, 34342, Turkey.
Gürkaslar C; Bogazici University, Department of Molecular Biology and Genetics, Molecular Toxicology and Cancer Research Laboratory, Bebek, Istanbul, 34342, Turkey.
Yaman I; Bogazici University, Department of Molecular Biology and Genetics, Molecular Toxicology and Cancer Research Laboratory, Bebek, Istanbul, 34342, Turkey; Bogazici University, Center for Life Sciences and Technologies, Bebek, Istanbul, 34342, Turkey. Electronic address: ibrahim.yaman@boun.edu.tr.

Toxicon ; 199: 79-86, 2021 Aug.

Article em En | MEDLINE | ID: mdl-34116085

Assuntos

Sistema de Sinalização das MAP Quinases; NF-kappa B; Animais; Apoptose; Linhagem Celular; Humanos; NF-kappa B/metabolismo; Ocratoxinas; Fosfatidilinositol 3-Quinases/metabolismo; Fosforilação

Palavras-chave

Apoptosis; HK-2 cell line; NF-κB; Ochratoxin A; p-ERK1/2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Sistema de Sinalização das MAP Quinases Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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