Using response surface models to analyze drug combinations.

Twarog, Nathaniel R; Martinez, Nancy E; Gartrell, Jessica; Xie, Jia; Tinkle, Christopher L; Shelat, Anang A

Twarog, Nathaniel R; Martinez, Nancy E; Gartrell, Jessica; Xie, Jia; Tinkle, Christopher L; Shelat, Anang A.

Afiliação

Twarog NR; Department of Chemical Biology and Therapeutics, St Jude Children's Research Hospital, Memphis, TN, USA.
Martinez NE; Department of Chemical Biology and Therapeutics, St Jude Children's Research Hospital, Memphis, TN, USA.
Gartrell J; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
Xie J; Department of Chemical Biology and Therapeutics, St Jude Children's Research Hospital, Memphis, TN, USA.
Tinkle CL; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
Shelat AA; Department of Chemical Biology and Therapeutics, St Jude Children's Research Hospital, Memphis, TN, USA. Electronic address: anang.shelat@stjude.org.

Drug Discov Today ; 26(8): 2014-2024, 2021 08.

Article em En | MEDLINE | ID: mdl-34119666

Assuntos

Desenvolvimento de Medicamentos/métodos; Modelos Teóricos; Viés; Interações Medicamentosas; Sinergismo Farmacológico; Quimioterapia Combinada; Humanos

Palavras-chave

Combination therapy; Response surface models; Synergy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenvolvimento de Medicamentos / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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