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European guideline on indications, performance and clinical impact of 13 C-breath tests in adult and pediatric patients: An EAGEN, ESNM, and ESPGHAN consensus, supported by EPC.
Keller, Jutta; Hammer, Heinz F; Afolabi, Paul R; Benninga, Marc; Borrelli, Osvaldo; Dominguez-Munoz, Enrique; Dumitrascu, Dan; Goetze, Oliver; Haas, Stephan L; Hauser, Bruno; Pohl, Daniel; Salvatore, Silvia; Sonyi, Marc; Thapar, Nikhil; Verbeke, Kristin; Fox, Mark R.
Afiliação
  • Keller J; Department of Internal Medicine, Israelitic Hospital, Academic Hospital University of Hamburg, Hamburg, Germany.
  • Hammer HF; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
  • Afolabi PR; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.
  • Benninga M; Department of Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Borrelli O; UCL Great Ormond Street Institute of Child Health and Department of Gastroenterology, Neurogastroenterology and Motility, Great Ormond Street Hospital, London, UK.
  • Dominguez-Munoz E; Department of Gastroenterology and Hepatology, University Hospital of Santiago de Compostela, Santiago, Spain.
  • Dumitrascu D; Clinica Medicala 2, Cluj-Napoca, Romania.
  • Goetze O; Department of Medicine II, Division of Hepatology, University Hospital Würzburg, Würzburg, Germany.
  • Haas SL; Department of Upper GI Diseases, Karolinska University Hospital, Stockholm, Sweden.
  • Hauser B; Department of Paediatric Gastroenterology, Hepatology and Nutrition, KidZ Health Castle UZ Brussels, Brussels, Belgium.
  • Pohl D; Division of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland.
  • Salvatore S; Pediatric Department, Hospital "F. Del Ponte", University of Insubria, Varese, Italy.
  • Sonyi M; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
  • Thapar N; Clinic for General Medicine, Gastroenterology, and Infectious Diseases, Augustinerinnen Hospital, Cologne, Germany.
  • Verbeke K; UCL Great Ormond Street Institute of Child Health and Department of Gastroenterology, Neurogastroenterology and Motility, Great Ormond Street Hospital, London, UK.
  • Fox MR; Department of Gastroenterology, Hepatology and Liver Transplantation, Queensland Children's Hospital, Brisbane, Australia.
United European Gastroenterol J ; 9(5): 598-625, 2021 06.
Article em En | MEDLINE | ID: mdl-34128346
INTRODUCTION: 13 C-breath tests are valuable, noninvasive diagnostic tests that can be widely applied for the assessment of gastroenterological symptoms and diseases. Currently, the potential of these tests is compromised by a lack of standardization regarding performance and interpretation among expert centers. METHODS: This consensus-based clinical practice guideline defines the clinical indications, performance, and interpretation of 13 C-breath tests in adult and pediatric patients. A balance between scientific evidence and clinical experience was achieved by a Delphi consensus that involved 43 experts from 18 European countries. Consensus on individual statements and recommendations was established if ≥ 80% of reviewers agreed and <10% disagreed. RESULTS: The guideline gives an overview over general methodology of 13 C-breath testing and provides recommendations for the use of 13 C-breath tests to diagnose Helicobacter pylori infection, measure gastric emptying time, and monitor pancreatic exocrine and liver function in adult and pediatric patients. Other potential applications of 13 C-breath testing are summarized briefly. The recommendations specifically detail when and how individual 13 C-breath tests should be performed including examples for well-established test protocols, patient preparation, and reporting of test results. CONCLUSION: This clinical practice guideline should improve pan-European harmonization of diagnostic approaches to symptoms and disorders, which are very common in specialist and primary care gastroenterology practice, both in adult and pediatric patients. In addition, this guideline identifies areas of future clinical research involving the use of 13 C-breath tests.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Função Pancreática / Testes Respiratórios / Helicobacter pylori / Infecções por Helicobacter / Consenso / Esvaziamento Gástrico / Testes de Função Hepática Tipo de estudo: Guideline / Prognostic_studies Limite: Adult / Child / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Função Pancreática / Testes Respiratórios / Helicobacter pylori / Infecções por Helicobacter / Consenso / Esvaziamento Gástrico / Testes de Função Hepática Tipo de estudo: Guideline / Prognostic_studies Limite: Adult / Child / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article