In-depth assessment of the PAM compatibility and editing activities of Cas9 variants.

Zhang, Weiwei; Yin, Jianhang; Zhang-Ding, Zhengrong; Xin, Changchang; Liu, Mengzhu; Wang, Yuhong; Ai, Chen; Hu, Jiazhi

Zhang, Weiwei; Yin, Jianhang; Zhang-Ding, Zhengrong; Xin, Changchang; Liu, Mengzhu; Wang, Yuhong; Ai, Chen; Hu, Jiazhi.

Afiliação

Zhang W; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Yin J; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Zhang-Ding Z; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Xin C; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Liu M; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Wang Y; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Ai C; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.
Hu J; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Center for Life Sciences, Genome Editing Research Center, Peking University, Beijing 100871, China.

Nucleic Acids Res ; 49(15): 8785-8795, 2021 09 07.

Article em En | MEDLINE | ID: mdl-34133740

Assuntos

Sistemas CRISPR-Cas/genética; Edição de Genes; Oryza/genética; Streptococcus pyogenes/enzimologia; Proteína 9 Associada à CRISPR/genética; Genoma de Planta/genética; Mutação/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oryza / Streptococcus pyogenes / Sistemas CRISPR-Cas / Edição de Genes Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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