Overcoming the senescence-associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer.

Chambers, Cecilia R; Ritchie, Shona; Pereira, Brooke A; Timpson, Paul

Chambers, Cecilia R; Ritchie, Shona; Pereira, Brooke A; Timpson, Paul.

Afiliação

Chambers CR; Garvan Institute of Medical Research, The Kinghorn Cancer Centre, Sydney, NSW, Australia.
Ritchie S; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.
Pereira BA; Garvan Institute of Medical Research, The Kinghorn Cancer Centre, Sydney, NSW, Australia.
Timpson P; Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.

Mol Oncol ; 15(12): 3242-3255, 2021 12.

Article em En | MEDLINE | ID: mdl-34137158

Assuntos

Antineoplásicos; Neoplasias; Carcinogênese; Senescência Celular; Humanos; Neoplasias/tratamento farmacológico; Neoplasias/metabolismo; Fenótipo; Fenótipo Secretor Associado à Senescência; Microambiente Tumoral

Palavras-chave

cancer; cellular senescence; senescence-associated secretory phenotype; therapy-induced senescence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias / Antineoplásicos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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