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Genome-scale CRISPR-Cas9 screen of Wnt/ß-catenin signaling identifies therapeutic targets for colorectal cancer.
Wan, Chunhua; Mahara, Sylvia; Sun, Claire; Doan, Anh; Chua, Hui Kheng; Xu, Dakang; Bian, Jia; Li, Yue; Zhu, Danxi; Sooraj, Dhanya; Cierpicki, Tomasz; Grembecka, Jolanta; Firestein, Ron.
Afiliação
  • Wan C; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Mahara S; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Sun C; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
  • Doan A; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Chua HK; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Xu D; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Bian J; Department of Molecular and Translational Science, Monash University, Clayton, VIC 3168, Australia.
  • Li Y; Faculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, 200025 Shanghai, China.
  • Zhu D; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Sooraj D; Faculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, 200025 Shanghai, China.
  • Cierpicki T; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Grembecka J; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
  • Firestein R; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
Sci Adv ; 7(21)2021 05.
Article em En | MEDLINE | ID: mdl-34138730
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Beta Catenina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Beta Catenina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article