Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins.

Sethi, Aaftaab; Sanam, Swetha; Alvala, Mallika

Sethi, Aaftaab; Sanam, Swetha; Alvala, Mallika.

Afiliação

Sethi A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India.
Sanam S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India.
Alvala M; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India; MARS Training Academy, Hyderabad, India. Electronic address: mallikaalvala@yahoo.in.

Eur J Med Chem ; 222: 113561, 2021 Oct 15.

Article em En | MEDLINE | ID: mdl-34146913

Assuntos

Galectinas/antagonistas & inibidores; Peptídeos/farmacologia; Relação Dose-Resposta a Droga; Galectinas/metabolismo; Estrutura Molecular; Peptídeos/química; Relação Estrutura-Atividade

Palavras-chave

Carbohydrates; Galectin inhibitors; Galectin-1; Galectin-3; Galectins; Lectins; Non-carbohydrate inhibitors; Sugar mimics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Galectinas Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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