Combination inhibition of triple-negative breast cancer cell growth with CD36 siRNA-loaded DNA nanoprism and genistein.

Wang, Beinuo; Yan, Ni; Wu, Di; Dou, Yin; Liu, Zhenyu; Hu, Xiaojuan; Chen, Cancan

Wang, Beinuo; Yan, Ni; Wu, Di; Dou, Yin; Liu, Zhenyu; Hu, Xiaojuan; Chen, Cancan.

Afiliação

Wang B; Queen Mary College, Medical School of Nanchang University, Nanchang 330006, People's Republic of China.
Yan N; Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Nanchang University, Nanchang 330006, People's Republic of China.
Wu D; Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, People's Republic of China.
Dou Y; Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, People's Republic of China.
Liu Z; Department of Pharmaceutics, College of Pharmacy, Third Military Medical University, Chongqing 400038, People's Republic of China.
Hu X; Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Nanchang University, Nanchang 330006, People's Republic of China.
Chen C; Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Nanchang University, Nanchang 330006, People's Republic of China.

Nanotechnology ; 32(39)2021 Jul 09.

Article em En | MEDLINE | ID: mdl-34153956

Assuntos

Antineoplásicos; Antígenos CD36/genética; Nanoestruturas/química; RNA Interferente Pequeno/genética; Neoplasias de Mama Triplo Negativas; Antineoplásicos/química; Antineoplásicos/metabolismo; Antineoplásicos/farmacologia; Antígenos CD36/metabolismo; Linhagem Celular Tumoral; DNA/química; Portadores de Fármacos/química; Portadores de Fármacos/metabolismo; Feminino; Genisteína/metabolismo; Genisteína/farmacologia; Humanos; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; RNA Interferente Pequeno/metabolismo; Proteínas Quinases p38 Ativadas por Mitógeno/genética; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

CD36 siRNA; DNA nanostructures; MDA-MB-231; combination therapy; genistein; phospho-p38 MAPK; triple-negative breast cancer cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD36 / RNA Interferente Pequeno / Nanoestruturas / Neoplasias de Mama Triplo Negativas / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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