Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size.
Clin Infect Dis
; 73(8): 1528-1531, 2021 10 20.
Article
em En
| MEDLINE
| ID: mdl-34181706
ABSTRACT
Understanding what shapes the latent human immunodeficiency virus type 1 (HIV-1) reservoir is critical for developing strategies for cure. We measured frequency of persistent HIV-1 infection after 5 years of suppressive antiretroviral therapy initiated during chronic infection. Pretreatment CD8+ T-cell activation, nadir CD4 count, and CD4CD8 ratio predicted reservoir size.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
HIV-1
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article