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Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Duan, Ruo-Nan; Yang, Chun-Lin; Du, Tong; Liu, Ai; Wang, An-Ran; Sun, Wen-Jie; Li, Xi; Li, Jiang-Xia; Yan, Chuan-Zhu; Liu, Qi-Ji.
Afiliação
  • Duan RN; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, Cheeloo College of Medicine, School of Basic Medical Sciences, Shandong University, No.44 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
  • Yang CL; Department of Neurology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
  • Du T; Department of Neurology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
  • Liu A; Department of Neurology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
  • Wang AR; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, Cheeloo College of Medicine, School of Basic Medical Sciences, Shandong University, No.44 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
  • Sun WJ; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, Cheeloo College of Medicine, School of Basic Medical Sciences, Shandong University, No.44 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
  • Li X; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, Cheeloo College of Medicine, School of Basic Medical Sciences, Shandong University, No.44 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
  • Li JX; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, Cheeloo College of Medicine, School of Basic Medical Sciences, Shandong University, No.44 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
  • Yan CZ; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, Cheeloo College of Medicine, School of Basic Medical Sciences, Shandong University, No.44 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
  • Liu QJ; Department of Neurology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
J Neuroinflammation ; 18(1): 145, 2021 Jun 28.
Article em En | MEDLINE | ID: mdl-34183017
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Interferon gama / Receptores de Hidrocarboneto Arílico / Microglia / Fosfoproteínas Fosfatases / Encefalomielite Autoimune Experimental / Indolamina-Pirrol 2,3,-Dioxigenase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Interferon gama / Receptores de Hidrocarboneto Arílico / Microglia / Fosfoproteínas Fosfatases / Encefalomielite Autoimune Experimental / Indolamina-Pirrol 2,3,-Dioxigenase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article