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Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness.
Pachano, Tomas; Sánchez-Gaya, Víctor; Ealo, Thais; Mariner-Faulí, Maria; Bleckwehl, Tore; Asenjo, Helena G; Respuela, Patricia; Cruz-Molina, Sara; Muñoz-San Martín, María; Haro, Endika; van IJcken, Wilfred F J; Landeira, David; Rada-Iglesias, Alvaro.
Afiliação
  • Pachano T; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Sánchez-Gaya V; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
  • Ealo T; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
  • Mariner-Faulí M; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
  • Bleckwehl T; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
  • Asenjo HG; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Respuela P; Centre for Genomics and Oncological Research (GENYO), Granada, Spain.
  • Cruz-Molina S; Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.
  • Muñoz-San Martín M; Instituto de Investigación Biosanitaria ibs.GRANADA, Hospital Virgen de las Nieves, Granada, Spain.
  • Haro E; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
  • van IJcken WFJ; Max Planck Institute for Molecular Biomedicine, Muenster, Germany.
  • Landeira D; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
  • Rada-Iglesias A; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria/SODERCAN, Santander, Spain.
Nat Genet ; 53(7): 1036-1049, 2021 07.
Article em En | MEDLINE | ID: mdl-34183853
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Elementos Facilitadores Genéticos / Ilhas de CpG / Metilação de DNA / Epigênese Genética Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Elementos Facilitadores Genéticos / Ilhas de CpG / Metilação de DNA / Epigênese Genética Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article