TMEM100 induces cell death in non­small cell lung cancer via the activation of autophagy and apoptosis.

He, Qian; Dong, Yilin; Zhu, Yiting; Ding, Zhiqiang; Zhang, Xinxin; Wang, Zimeng; Ai, Rongshuang; He, Yujuan

TMEM100 induces cell death in nonsmall cell lung cancer via the activation of autophagy and apoptosis.

He, Qian; Dong, Yilin; Zhu, Yiting; Ding, Zhiqiang; Zhang, Xinxin; Wang, Zimeng; Ai, Rongshuang; He, Yujuan.

Afiliação

He Q; Department of Laboratory Medicine, Key Laboratory of Diagnostic Medicine (Ministry of Education), Chongqing Medical University, Chongqing 400016, P.R. China.
Dong Y; Department of Laboratory Medicine, Key Laboratory of Diagnostic Medicine (Ministry of Education), Chongqing Medical University, Chongqing 400016, P.R. China.
Zhu Y; Department of Laboratory Medicine, Key Laboratory of Diagnostic Medicine (Ministry of Education), Chongqing Medical University, Chongqing 400016, P.R. China.
Ding Z; School of Computer Science, Chongqing Institute of Engineering, Chongqing 401300, P.R. China.
Zhang X; Department of Laboratory Medicine, Key Laboratory of Diagnostic Medicine (Ministry of Education), Chongqing Medical University, Chongqing 400016, P.R. China.
Wang Z; Department of Laboratory Medicine, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, P.R. China.
Ai R; Department of Laboratory Medicine, Key Laboratory of Diagnostic Medicine (Ministry of Education), Chongqing Medical University, Chongqing 400016, P.R. China.
He Y; Department of Laboratory Medicine, Key Laboratory of Diagnostic Medicine (Ministry of Education), Chongqing Medical University, Chongqing 400016, P.R. China.

Oncol Rep ; 45(5)2021 05.

Article em En | MEDLINE | ID: mdl-34184748

Assuntos

Carcinoma Pulmonar de Células não Pequenas/metabolismo; Neoplasias Pulmonares/metabolismo; Proteínas de Membrana/biossíntese; Células A549; Adenocarcinoma de Pulmão/metabolismo; Adenocarcinoma de Pulmão/patologia; Animais; Apoptose/fisiologia; Autofagia/fisiologia; Western Blotting; Carcinoma Pulmonar de Células não Pequenas/patologia; Estudos de Casos e Controles; Linhagem Celular Tumoral; Feminino; Xenoenxertos; Humanos; Neoplasias Pulmonares/patologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/antagonistas & inibidores; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais

Palavras-chave

NSCLC; TMEM100; apoptosis; autophagy; tumor suppressor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares / Proteínas de Membrana Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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