Crystal structure of clinically reported mutations Gly656Arg, Gly656Glu and Asp751His identified in the kinase domain of EphA7.

Chakraborty, Shubhashish; Varma, Ashok K

Chakraborty, Shubhashish; Varma, Ashok K.

Afiliação

Chakraborty S; Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai, Maharashtra, 410210, India; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra, 400094, India.
Varma AK; Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai, Maharashtra, 410210, India; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra, 400094, India. Electronic address: avarma@actrec.gov.in.

Biochem Biophys Res Commun ; 568: 62-67, 2021 09 03.

Article em En | MEDLINE | ID: mdl-34186436

Assuntos

Mutação Puntual; Receptor EphA7/química; Receptor EphA7/genética; Cristalografia por Raios X; Humanos; Modelos Moleculares; Conformação Proteica; Domínios Proteicos

Palavras-chave

Crystal structure; Erythropoietin producing hepatocellular (Eph); Mutations; RTKs; Structural alterations

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação Puntual / Receptor EphA7 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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