SARS-CoV-2 transmissions in students and teachers: seroprevalence follow-up study in a German secondary school in November and December 2020.
BMJ Paediatr Open
; 5(1): e001036, 2021.
Article
em En
| MEDLINE
| ID: mdl-34192197
ABSTRACT
Objective:
To quantify the number of undetected SARS-CoV-2 infections in educational settings.Design:
Serial SARS-CoV-2 seroprevalence study before and during the second wave of the COVID-19 pandemic.Setting:
Secondary school in Dresden, Germany.Participants:
Grade 8-12 students and their teachers were invited to participate in serial blood sampling and SARS-CoV-2 IgG antibody assessment. Main outcomemeasure:
Seroprevalence of SARS-CoV-2 antibodies in study population.Results:
247 students and 55 teachers participated in the initial study visit and 197 students and 40 teachers completed follow-up. Seroprevalence increased from 1.7% (0.3-3.3) to 6.8% (3.8-10.1) during the study period mirroring the increase of officially reported SARS-CoV-2 infections during this time. The ratio of undetected to detected SARS-CoV-2 infections ranged from 0.25 to 0.33.Conclusions:
We could not find evidence of relevant silent, asymptomatic spread of SARS-CoV-2 in schools neither in a low prevalence setting nor during the second wave of the pandemic, making it unlikely that educational settings play a crucial role in driving the SARS-CoV-2 pandemic. Trial registration number DRKS00022455.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
SARS-CoV-2
/
COVID-19
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article