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Chemoproteomic Study Uncovers HemK2/KMT9 As a New Target for NTMT1 Bisubstrate Inhibitors.
Chen, Dongxing; Meng, Ying; Yu, Dan; Noinaj, Nicholas; Cheng, Xiaodong; Huang, Rong.
Afiliação
  • Chen D; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
  • Meng Y; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
  • Yu D; Department of Epigenetics and Molecular Carcinogenesis, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, United States.
  • Noinaj N; Department of Biological Sciences, Markey Center for Structural Biology, and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana 47907, United States.
  • Cheng X; Department of Epigenetics and Molecular Carcinogenesis, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, United States.
  • Huang R; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
ACS Chem Biol ; 16(7): 1234-1242, 2021 07 16.
Article em En | MEDLINE | ID: mdl-34192867
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / DNA Metiltransferases Sítio Específica (Adenina-Específica) / Adenosina / Inibidores Enzimáticos / Metiltransferases Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / DNA Metiltransferases Sítio Específica (Adenina-Específica) / Adenosina / Inibidores Enzimáticos / Metiltransferases Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article