Electrophysiological and Structural Remodeling of the Atria in a Mouse Model of Troponin-I Mutation Linked Hypertrophic Cardiomyopathy: Implications for Atrial Fibrillation.

Lim, Wei-Wen; Neo, Melissa; Thanigaimani, Shivshankar; Kuklik, Pawel; Ganesan, Anand N; Lau, Dennis H; Tsoutsman, Tatiana; Kalman, Jonathan M; Semsarian, Christopher; Saint, David A; Sanders, Prashanthan

Lim, Wei-Wen; Neo, Melissa; Thanigaimani, Shivshankar; Kuklik, Pawel; Ganesan, Anand N; Lau, Dennis H; Tsoutsman, Tatiana; Kalman, Jonathan M; Semsarian, Christopher; Saint, David A; Sanders, Prashanthan.

Afiliação

Lim WW; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Neo M; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore 169609, Singapore.
Thanigaimani S; Programme in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Kuklik P; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Ganesan AN; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Lau DH; The Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry and The Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, Australia.
Tsoutsman T; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Kalman JM; Department of Cardiology, Asklepios Klinik St. Georg, 20099 Hamburg, Germany.
Semsarian C; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Saint DA; Department of Cardiovascular Medicine, Flinders Medical Centre, Bedford Park, SA 5042, Australia.
Sanders P; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Royal Adelaide Hospital, Adelaide, SA 5000, Australia.

Int J Mol Sci ; 22(13)2021 Jun 28.

Article em En | MEDLINE | ID: mdl-34203369

Assuntos

Fibrilação Atrial/metabolismo; Cardiomiopatia Hipertrófica/metabolismo; Átrios do Coração/metabolismo; Troponina I/metabolismo; Potenciais de Ação/fisiologia; Animais; Fibrilação Atrial/genética; Remodelamento Atrial/genética; Remodelamento Atrial/fisiologia; Pressão Sanguínea/fisiologia; Eletrofisiologia Cardíaca; Cardiomiopatia Hipertrófica/genética; Modelos Animais de Doenças; Eletrofisiologia; Feminino; Átrios do Coração/patologia; Frequência Cardíaca/fisiologia; Humanos; Masculino; Mutação; Troponina I/genética

Palavras-chave

atrial fibrillation; electrophysiology; histology; hypertrophic cardiomyopathy; mice

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Cardiomiopatia Hipertrófica / Troponina I / Átrios do Coração Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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