The Promising Effect of Peucedanum chenur Chloroformic Extract on Prevention of Human Colorectal Cancer Progression by Modulating miR-135b, miR-21, and APC Genes.

Fadaei, Milad; Amini, Razieh; Dastan, Dara; Eslami, Hamid; Mahdavinezhad, Ali

Fadaei, Milad; Amini, Razieh; Dastan, Dara; Eslami, Hamid; Mahdavinezhad, Ali.

Afiliação

Fadaei M; Department of Molecular Medicine & Genetics, Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Amini R; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Dastan D; Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Eslami H; Department of Pharmacognosy and Pharmaceutical Biotechnology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
Mahdavinezhad A; Department of Molecular Medicine & Genetics, Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

J Gastrointest Cancer ; 53(3): 549-556, 2022 Sep.

Article em En | MEDLINE | ID: mdl-34212311

Assuntos

Neoplasias Colorretais; MicroRNAs; Proteína da Polipose Adenomatosa do Colo; Antioxidantes/farmacologia; Antioxidantes/uso terapêutico; Linhagem Celular Tumoral; Proliferação de Células/genética; Clorofórmio/uso terapêutico; Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Regulação Neoplásica da Expressão Gênica; Genes APC; Humanos; MicroRNAs/genética; MicroRNAs/metabolismo

Palavras-chave

APC; Colorectal neoplasms; HCT-116 cell line; Peucedanum chenur; miR-135b; miR-21

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / MicroRNAs Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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