Discovery of phloroglucinols from Hypericum japonicum as ferroptosis inhibitors.

Peng, Xing; Tan, Qingyun; Zhou, Huihao; Xu, Jun; Gu, Qiong

Peng, Xing; Tan, Qingyun; Zhou, Huihao; Xu, Jun; Gu, Qiong.

Afiliação

Peng X; Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Tan Q; Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Zhou H; Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Xu J; Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Gu Q; Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China. Electronic address: guqiong@mail.sysu.edu.cn.

Fitoterapia ; 153: 104984, 2021 Sep.

Article em En | MEDLINE | ID: mdl-34216691

Assuntos

Antioxidantes/farmacologia; Ferroptose/efeitos dos fármacos; Hypericum/química; Floroglucinol/farmacologia; Animais; Antioxidantes/isolamento & purificação; Linhagem Celular; China; Camundongos; Estrutura Molecular; Floroglucinol/isolamento & purificação; Compostos Fitoquímicos/isolamento & purificação; Compostos Fitoquímicos/farmacologia

Palavras-chave

Antioxidant effect; Ferroptosis inhibitor; Hypericum japonicum; Phloroglucinols

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Floroglucinol / Hypericum / Ferroptose / Antioxidantes Limite: Animals País/Região como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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