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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress.
Nüchel, Julian; Tauber, Marina; Nolte, Janica L; Mörgelin, Matthias; Türk, Clara; Eckes, Beate; Demetriades, Constantinos; Plomann, Markus.
Afiliação
  • Nüchel J; Max Planck Institute for Biology of Ageing (MPI-AGE), 50931 Cologne, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Biochemistry, 50931 Cologne, Germany.
  • Tauber M; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Biochemistry, 50931 Cologne, Germany.
  • Nolte JL; University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany.
  • Mörgelin M; Colzyx AB, Medicon Village, 223 63 Lund, Sweden.
  • Türk C; University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany.
  • Eckes B; University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Matrix Biology, 50931 Cologne, Germany.
  • Demetriades C; Max Planck Institute for Biology of Ageing (MPI-AGE), 50931 Cologne, Germany; University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany. Electronic address: demetriades@age.mpg.de.
  • Plomann M; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Biochemistry, 50931 Cologne, Germany. Electronic address: markus.plomann@uni-koeln.de.
Mol Cell ; 81(16): 3275-3293.e12, 2021 08 19.
Article em En | MEDLINE | ID: mdl-34245671

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Proteoma / Proteômica / Proteínas da Matriz do Complexo de Golgi Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Proteoma / Proteômica / Proteínas da Matriz do Complexo de Golgi Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article