Biochemical properties of fission yeast homologous recombination enzymes.
Curr Opin Genet Dev
; 71: 19-26, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-34246071
ABSTRACT
Homologous recombination (HR) is a universal phenomenon conserved from viruses to humans. The mechanisms of HR are essentially the same in humans and simple unicellular eukaryotes like yeast. Two highly diverged yeast species, Saccharomyces cerevisiae and Schizosaccharomyces pombe, have proven exceptionally useful in understanding the fundamental mechanisms of eukaryotic HR by serving as a source for unique biological insights and also complementing each other. Here, we will review the features of S. pombe HR mechanisms in comparison to S. cerevisiae and other model organisms. Particular emphasis will be put on the biochemical characterization of HR mechanisms uncovered using S. pombe proteins.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Schizosaccharomyces
/
Proteínas de Schizosaccharomyces pombe
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article