Overexpression of excision repair cross-complementing 1 gene associates with higher risk of therapeutic failure after definitive chemoradiation for unresectable non-small cell lung cancer.

Deek, Matthew P; Yegya-Raman, Nikhil; Daroui, Parima; Balasubramanian, Sairam; Malhotra, Jyoti; Moore, Dirk; Patel, Malini; Wang, Shang-Jui; Aisner, Joseph; Jabbour, Salma K

Deek, Matthew P; Yegya-Raman, Nikhil; Daroui, Parima; Balasubramanian, Sairam; Malhotra, Jyoti; Moore, Dirk; Patel, Malini; Wang, Shang-Jui; Aisner, Joseph; Jabbour, Salma K.

Afiliação

Deek MP; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yegya-Raman N; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Daroui P; Department of Radiation Oncology, The Permanente Medical Group, Santa Clara Cancer Treatment Center, Santa Clara, CA, USA.
Balasubramanian S; Department of Emergency Medicine, Sinai Hospital Baltimore, Baltimore, MD, USA.
Malhotra J; Department of Medical Oncology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
Moore D; Department of Biostatistics and Epidemiology, Rutgers University, NJ, USA.
Patel M; Department of Medical Oncology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
Wang SJ; Department of Radiation Oncology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
Aisner J; Department of Medical Oncology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
Jabbour SK; Department of Radiation Oncology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.

Ann Palliat Med ; 10(7): 7205-7213, 2021 Jul.

Article em En | MEDLINE | ID: mdl-34263627

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/terapia; Reparo do DNA/genética; Proteínas de Ligação a DNA/genética; Proteínas de Ligação a DNA/metabolismo; Endonucleases/genética; Endonucleases/metabolismo; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/terapia; Prognóstico; Resultado do Tratamento

Palavras-chave

Excision repair cross-complementing 1 (ERCC1); chemoradiation; lung cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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