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Renal Resistive Index as a Predictor of Acute Kidney Injury and Mortality in COVID-19 Critically Ill Patients.
Cruz, Edgar Garcia; Broca Garcia, Blanca Estela; Sandoval, Daniel Manzur; Gopar-Nieto, Rodrigo; Gonzalez Ruiz, Francisco Javier; Gallardo, Linda Diaz; Ronco, Claudio; Madero, Magdalena; Vasquez Jimenez, Enzo.
Afiliação
  • Cruz EG; Department of Cardiovascular Critical Care, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
  • Broca Garcia BE; Department of Cardiology, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
  • Sandoval DM; Department of Cardiovascular Critical Care, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
  • Gopar-Nieto R; Department of Cardiology, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
  • Gonzalez Ruiz FJ; Department of Cardiovascular Critical Care, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
  • Gallardo LD; Department of Pediatrics, Sanatorio Durango, Mexico City, Mexico.
  • Ronco C; Department of Nephrology, San Bortolo Hospital and International Renal Research Institute of Vicenza (IRRIV), Vicenza, Italy.
  • Madero M; Department of Nephrology, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
  • Vasquez Jimenez E; Department of Nephrology, Nacional Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
Blood Purif ; 51(4): 309-316, 2022.
Article em En | MEDLINE | ID: mdl-34280921
BACKGROUND: Acute kidney injury (AKI) in patients with COVID-19 can be caused by multiple mechanisms. Renal resistive index (RRI) is a noninvasive instrument to evaluate kidney hemodynamics, and it is obtained by analysis of intrarenal arterial waves using Doppler ultrasound. This study aimed to determine the role of RRI in predicting AKI and adverse outcomes in critically ill patients with COVID-19. METHODS: This cross-sectional study included 65 patients with confirmed SARS-CoV-2 pneumonia admitted to the critical care unit from April 1, 2020, to June 20, 2020. Informed consent was obtained from all individual participants included in the study. Cardiac, pulmonary, and kidney ultrasonographic evaluations were performed in a protocolized way. RESULTS: In this cohort, 65 patients were included, mean age was 53.4 years, 79% were male, and 35% were diabetic. Thirty-four percent of patients developed AKI, 12% required RRT, and 35% died. Of the patients who developed AKI, 68% had RRI ≥ 0.7. Also, 75% of the patients who required RRT had RRI ≥ 0.7. In the adjusted Cox model, the RRI ≥ 0.7 was associated with higher mortality (HR 2.86, 95% CI: 1.19-6.82, p = 0.01). CONCLUSIONS: Critical care ultrasonography is a noninvasive, reproducible, and accurate bedside method that has proven its usefulness. An elevated RRI may have a role in predicting AKI, RRT initiation, and mortality in patients with severe SARS-CoV-2 pneumonia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Injúria Renal Aguda / COVID-19 Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Injúria Renal Aguda / COVID-19 Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article