TrkB/BDNF Signaling Could Be a New Therapeutic Target for Pancreatic Cancer.

Oyama, Yasuhiro; Nagao, Shinjiro; Na, Lin; Yanai, Kosuke; Umebayashi, Masayo; Nakamura, Katsuya; Nagai, Shuntaro; Fujimura, Akiko; Yamasaki, Akio; Nakayama, Kazunori; Morisaki, Takashi; Onishi, Hideya

Oyama, Yasuhiro; Nagao, Shinjiro; Na, Lin; Yanai, Kosuke; Umebayashi, Masayo; Nakamura, Katsuya; Nagai, Shuntaro; Fujimura, Akiko; Yamasaki, Akio; Nakayama, Kazunori; Morisaki, Takashi; Onishi, Hideya.

Afiliação

Oyama Y; Departments of Cancer Therapy and Research, Kyushu University, Fukuoka, Japan.
Nagao S; Departments of Cancer Therapy and Research, Kyushu University, Fukuoka, Japan.
Na L; Departments of Cancer Therapy and Research, Kyushu University, Fukuoka, Japan.
Yanai K; Departments of Surgery and Oncologys, Kyushu University, Fukuoka, Japan.
Umebayashi M; Fukuoka General Cancer Clinic, Fukuoka, Japan.
Nakamura K; Departments of Surgery and Oncologys, Kyushu University, Fukuoka, Japan.
Nagai S; Departments of Surgery and Oncologys, Kyushu University, Fukuoka, Japan.
Fujimura A; Departments of Cancer Therapy and Research, Kyushu University, Fukuoka, Japan.
Yamasaki A; Departments of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nakayama K; Departments of Cancer Therapy and Research, Kyushu University, Fukuoka, Japan.
Morisaki T; Departments of Cancer Therapy and Research, Kyushu University, Fukuoka, Japan.
Onishi H; Fukuoka General Cancer Clinic, Fukuoka, Japan.

Anticancer Res ; 41(8): 4047-4052, 2021 Aug.

Article em En | MEDLINE | ID: mdl-34281873

Assuntos

Fator Neurotrófico Derivado do Encéfalo/metabolismo; Carcinoma Ductal Pancreático/metabolismo; Glicoproteínas de Membrana/metabolismo; Neoplasias Pancreáticas/metabolismo; Receptor trkB/metabolismo; Fator Neurotrófico Derivado do Encéfalo/genética; Carbazóis/farmacologia; Carcinoma Ductal Pancreático/patologia; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Humanos; Alcaloides Indólicos/farmacologia; Glicoproteínas de Membrana/antagonistas & inibidores; Glicoproteínas de Membrana/genética; Neoplasias Pancreáticas/patologia; Inibidores de Proteínas Quinases/farmacologia; Interferência de RNA; RNA Interferente Pequeno/genética; Receptor trkB/antagonistas & inibidores; Receptor trkB/genética; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

BDNF; TrkB; invasion; pancreatic cancer; proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Glicoproteínas de Membrana / Fator Neurotrófico Derivado do Encéfalo / Receptor trkB / Carcinoma Ductal Pancreático Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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