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PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer.
Lee, Emily; Szvetecz, Sarah; Polli, Ryan; Grauel, Angelo; Chen, Jayson; Judge, Joyce; Jaiswal, Smita; Maeda, Rie; Schwartz, Stephanie; Voedisch, Bernd; Piksa, Mateusz; Japutra, Chietara; Sadhasivam, Lingheswar; Wang, Yiqin; Carrion, Ana; Isim, Sinan; Liang, Jinsheng; Nicholson, Thomas; Lei, Hong; Fang, Qing; Steinkrauss, Michelle; Walker, Dana; Wagner, Joel; Cremasco, Viviana; Wang, Hui Qin; Galli, Giorgio G; Granda, Brian; Mansfield, Keith; Simmons, Quincey; Nguyen, Andrew Anh; Vincent Jordan, Nicole.
Afiliação
  • Lee E; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Szvetecz S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Polli R; PKS Oncology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Grauel A; Immuno-Oncology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Chen J; PCS Toxicology, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
  • Judge J; PCS Toxicology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Jaiswal S; PCS Toxicology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Maeda R; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Schwartz S; Immuno-Oncology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Voedisch B; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Piksa M; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Japutra C; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Sadhasivam L; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Wang Y; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Carrion A; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Isim S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Liang J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Nicholson T; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Lei H; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Fang Q; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Steinkrauss M; PCS Toxicology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Walker D; PCS Toxicology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Wagner J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Cremasco V; Immuno-Oncology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Wang HQ; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Galli GG; Oncology, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Granda B; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Mansfield K; PCS Toxicology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Simmons Q; PCS Toxicology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Nguyen AA; NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA. anh.nguyen@novartis.com.
  • Vincent Jordan N; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. nicole.vincentjordan@gmail.com.
Sci Rep ; 11(1): 14841, 2021 07 21.
Article em En | MEDLINE | ID: mdl-34290299
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Linfócitos T / Anticorpos Biespecíficos / Proteínas Supressoras de Tumor / Fator de Transcrição PAX8 / Imunoterapia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Linfócitos T / Anticorpos Biespecíficos / Proteínas Supressoras de Tumor / Fator de Transcrição PAX8 / Imunoterapia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article