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A single dose of anti-IL-1ß antibodies prevents Western diet-induced immune activation during early stage collagenase-induced osteoarthritis, but does not ameliorate end-stage pathology.
Kruisbergen, N N L; van Gemert, Y; Walgreen, B; Helsen, M M A; Slöetjes, A W; Koenders, M I; van de Loo, F A J; Roth, J; Vogl, T; van der Kraan, P M; Blom, A B; van den Bosch, M H J; van Lent, P L E M.
Afiliação
  • Kruisbergen NNL; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Nik.Kruisbergen@radboudumc.nl.
  • van Gemert Y; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Yvonne.vanGemert@radboudumc.nl.
  • Walgreen B; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Birgitte.Walgreen@radboudumc.nl.
  • Helsen MMA; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Monique.Helsen@radboudumc.nl.
  • Slöetjes AW; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Annet.Sloetjes@radboudumc.nl.
  • Koenders MI; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Marije.Koenders@radboudumc.nl.
  • van de Loo FAJ; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Fons.vandeLoo@radboudumc.nl.
  • Roth J; Institute of Immunology, University of Münster, Germany. Electronic address: rothj@uni-muenster.de.
  • Vogl T; Institute of Immunology, University of Münster, Germany. Electronic address: vogl@uni-muenster.de.
  • van der Kraan PM; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Peter.vanderKraan@radboudumc.nl.
  • Blom AB; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Arjen.Blom@radboudumc.nl.
  • van den Bosch MHJ; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Martijn.vandenBosch@radboudumc.nl.
  • van Lent PLEM; Experimental Rheumatology, Department of Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Peter.vanLent@radboudumc.nl.
Osteoarthritis Cartilage ; 29(10): 1462-1473, 2021 10.
Article em En | MEDLINE | ID: mdl-34298196
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Interleucina-1beta / Dieta Ocidental / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Interleucina-1beta / Dieta Ocidental / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article