[Changes of carotid artery elasticity before and after CPAP in patients with obstructive sleep apnea by ultrasonic ultrafast pulse wave velocity technique].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
; 35(8): 707-711, 2021 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-34304531
ABSTRACT
Objective:
To examine the changes of carotid artery elasticity in patients with obstructive sleep apneaï¼OSAï¼ before and after continuous positive airway pressureï¼CPAPï¼ treatment by ultrafast pulse wave velocityï¼UFPWVï¼ techniqueï¼and to explore the influencing factors of carotid artery elasticity in OSA patientsï¼and to provide guidance for clinical prevention and treatment of cardiovascular complications. Methodsï¼Fifty cases of moderate and severe OSA patients diagnosed with PSG monitoring from January 2020 to December 2020 were collected as the OSA groupï¼at the same timeï¼40 healthy subjects who participated in physical examination and matched with OSA group in age and gender were selected as the control group.The OSA group was treated with CPAP for 12 weeks.Clinical indicatorsï¼carotid intima-media thicknessï¼IMTï¼ï¼and pulse wave velocity at the beginning of systoleï¼PWVBSï¼ and pulse wave velocity at the end of systoleï¼PWVESï¼ were recorded in the control groupï¼and the above data were collected in the OSA group before and after treatment.The changes of various indicators between the control group and the OSA groupï¼and between the OSA group before and after treatment were compared.The correlative factors and influencing factors of PWVBS and PWVES are analyzed. Resultsï¼The serum lipid indexesï¼IMTï¼PWVBS and PWVES in OSA group were higher than those in control groupï¼P<0.05ï¼.Comparison between post-treatment and pre-treatment with CPAP in OSA groupï¼PWVBSï¼PWVESï¼apnea hypopnea indexï¼AHIï¼ï¼blood oxygen saturationï¼SaO2ï¼ less than 90% of the timeï¼the percentage of monitoring time when SaO2 was less than 90%ï¼T90ï¼ï¼low density lipoprotein cholesterolï¼LDL-Cï¼and triglycerideï¼TGï¼ were decreasedï¼P<0.05ï¼.Lowest blood oxygen saturationï¼LSaO2ï¼ and high density lipoprotein cholesterolï¼HDL-Cï¼ increasedï¼P<0.05ï¼.Ageï¼systolic blood pressureï¼IMTï¼AHIï¼T90 and time of oxygen saturation below 90% were positively correlated with PWVBS and PWVESï¼while HDL-C and LSaO2 were negatively correlated with themï¼P<0.05ï¼.The risk factors of PWVBS and PWVES included systolic blood pressureï¼AHIï¼TCï¼T90.Conclusionï¼Moderate and severe OSA can reduce arterial elasticity.CPAP can improve carotid artery elasticity function in patients with OSA.UFPWV technique is more sensitive to quantitatively evaluate the changes of arterial elasticity in patients with OSA than traditional two-dimensional ultrasound.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apneia Obstrutiva do Sono
/
Pressão Positiva Contínua nas Vias Aéreas
Tipo de estudo:
Guideline
/
Risk_factors_studies
Limite:
Humans
/
Infant
Idioma:
Zh
Ano de publicação:
2021
Tipo de documento:
Article