RAAS, ACE2 and COVID-19; a mechanistic review.

Elshafei, Ahmed; Khidr, Emad Gamil; El-Husseiny, Ahmed A; Gomaa, Maher H

Elshafei, Ahmed; Khidr, Emad Gamil; El-Husseiny, Ahmed A; Gomaa, Maher H.

Afiliação

Elshafei A; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Nasr City 11231, Cairo, Egypt.
Khidr EG; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Nasr City 11231, Cairo, Egypt.
El-Husseiny AA; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Nasr City 11231, Cairo, Egypt.
Gomaa MH; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Nasr City 11231, Cairo, Egypt.

Saudi J Biol Sci ; 28(11): 6465-6470, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34305426

Palavras-chave

ACE1, angiotensin-converting enzyme 1; ACE2; ACE2, angiotensin-converting enzyme 2; ACEIs; ACEIs, angiotensin-converting enzyme inhibitors; AEC-II, alveolar epithelial type II cells; ARBs; ARBs, angiotensin receptor blockers; AT1R, angiotensin type 1 receptor; AT2R, angiotensin type 2 receptor; Ang 1-7, angiotensin 1-7; Ang 1-9, angiotensin 1-9; AngI, angiotensin I; AngII, angiotensin II; Angiotensin 17; Angiotensin II; COVID-19; COVID-19, coronavirus disease 2019; CVD, cardiovascular disease; ERK, extracellular signal-regulated kinase; ICU, intensive care unit; MAPK, mitogen-activated protein kinase; NLRP3, (NOD, LRR, and pyrin domain-containing protein 3); RAAS, renin-angiotensin-aldosterone system; TGF-ß, transforming growth factor-beta; miR-21, microRNA-21

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article