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Menopausal status, age and management among women living with HIV in the UK.
Okhai, Hajra; Sabin, Caroline A; Haag, Katharina; Sherr, Lorraine; Dhairyawan, Rageshri; Burns, Fiona; Gilson, Richard; Post, Frank; Ross, Jonathan; Mackie, Nicola; Sullivan, Ann; Shepherd, Jane; Tariq, Anjum; Jones, Rachael; Fox, Julie; Rosenvinge, Melanie; Tariq, Shema.
Afiliação
  • Okhai H; Institute for Global Health, University College London, London, UK.
  • Sabin CA; Institute for Global Health, University College London, London, UK.
  • Haag K; Institute for Global Health, University College London, London, UK.
  • Sherr L; Institute for Global Health, University College London, London, UK.
  • Dhairyawan R; Department of Infection and Immunity, Barts Health NHS Trust, London, UK.
  • Burns F; Institute for Global Health, University College London, London, UK.
  • Gilson R; Royal Free London NHS Foundation Trust, London, UK.
  • Post F; Institute for Global Health, University College London, London, UK.
  • Ross J; King's College Hospital NHS Foundation Trust, London, UK.
  • Mackie N; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
  • Sullivan A; Imperial College Healthcare NHS Trust, London, UK.
  • Shepherd J; Chelsea and Westminster Healthcare NHS Foundation Trust, London, UK.
  • Tariq A; UK Community Advisory Board, London, UK.
  • Jones R; The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
  • Fox J; Chelsea and Westminster Healthcare NHS Foundation Trust, London, UK.
  • Rosenvinge M; King's College Hospital NHS Foundation Trust, London, UK.
  • Tariq S; Lewisham and Greenwich NHS Trust, London, UK.
HIV Med ; 22(9): 834-842, 2021 10.
Article em En | MEDLINE | ID: mdl-34309177
BACKGROUND: There is currently little evidence exploring menopausal status, age at last menstrual period (LMP) and management of menopause among women living with HIV aged 45-60 years in England. METHODS: Socio-demographic, lifestyle and clinical data were collected through a self-completed cross-sectional survey. Longitudinal CD4 count and viral load data were available from linkage to clinical records, if consent was provided. Women were categorised as pre-, peri- or post-menopausal. Factors associated with menopausal stage were examined using ordinal logistic regression adjusting for age. Age at LMP was estimated using Kaplan-Meier survival analysis. RESULTS: The 847 women had a median age of 49 [interquartile range (IQR): 47-52] years. Most were of black ethnicity (81.3%), were born outside the UK (85.0%) and had completed secondary education (88.7%); 177 (20.4%), 373 (43.0%) and 297 (34.2%) were pre-, peri- or post-menopausal, respectively. After adjusting for age, associations of menopausal status with non-cohabiting relationship [adjusted odds ratio = 0.63 (95% confidence interval: 0.43-0.91)], baseline viral load ≥ 100 000 copies/mL [2.67 (1.20-5.94)] and unemployment [1.34 (0.97-1.84)] remained significant. Median (IQR) age at LMP was 54 (51-55) years in the group. In total, 27.9% (233/836) of women reported severe menopausal symptoms; 45.6% of those with somatic symptoms had heard of hormone replacement therapy and 8.7% had used it. Only 5.6% of women with urogenital symptoms had used topical oestrogen. CONCLUSIONS: Our findings highlight the importance of educating both women and their healthcare providers about menopausal symptoms and management options.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article