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MEK inhibition ameliorates social behavior phenotypes in a Spred1 knockout mouse model for RASopathy disorders.
Borrie, Sarah C; Plasschaert, Ellen; Callaerts-Vegh, Zsuzsanna; Yoshimura, Akihiko; D'Hooge, Rudi; Elgersma, Ype; Kushner, Steven A; Legius, Eric; Brems, Hilde.
Afiliação
  • Borrie SC; Department of Human Genetics, KU Leuven, O&N1 Herestraat 49, Box 607, 3000, Leuven, Belgium.
  • Plasschaert E; Department of Human Genetics, KU Leuven, O&N1 Herestraat 49, Box 607, 3000, Leuven, Belgium.
  • Callaerts-Vegh Z; Laboratory for Biological Psychology, KU Leuven, Leuven, Belgium.
  • Yoshimura A; Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
  • D'Hooge R; Laboratory for Biological Psychology, KU Leuven, Leuven, Belgium.
  • Elgersma Y; ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Kushner SA; Department of Neuroscience, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Legius E; ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Brems H; Department of Psychiatry, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Mol Autism ; 12(1): 53, 2021 07 26.
Article em En | MEDLINE | ID: mdl-34311771

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromina 1 / Transtorno do Espectro Autista Tipo de estudo: Guideline / Prognostic_studies Limite: Adult / Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromina 1 / Transtorno do Espectro Autista Tipo de estudo: Guideline / Prognostic_studies Limite: Adult / Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article