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Selection and Characterization of FD164, a High-Affinity Signal Regulatory Protein α Variant with Balanced Safety and Effectiveness, from a Targeted Epitope Mammalian Cell-Displayed Antibody Library.
Wang, Zhihong; Hu, Naijing; Li, Xinying; Wang, Haitao; Ren, Caiping; Qiao, Chunxia; Chen, Guojiang; Wang, Jing; Zhou, Liuzhong; Wu, Jiaguo; Zhang, Dingmu; Feng, Jiannan; Shen, Beifen; Peng, Hui; Luo, Longlong.
Afiliação
  • Wang Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Hu N; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Li X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Wang H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Ren C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Qiao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Chen G; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Wang J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Zhou L; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Wu J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Zhang D; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Feng J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Shen B; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Peng H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
  • Luo L; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China (Z.W., N.H., X.L., C.Q., G.C., J.W., L.Z., J.W., D.Z., J.F., B.S., L.L.); School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China (
Mol Pharmacol ; 100(3): 193-202, 2021 09.
Article em En | MEDLINE | ID: mdl-34315811
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Imunológicos / Antígenos de Diferenciação / Antígeno CD47 Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Imunológicos / Antígenos de Diferenciação / Antígeno CD47 Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article