Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease.
JACC Case Rep
; 1(2): 171-174, 2019 Aug.
Article
em En
| MEDLINE
| ID: mdl-34316778
ABSTRACT
A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I. Heart catheterization showed normal coronaries and biopsy-proven, virus-negative lymphocytic myocarditis. A biopsy-guided immunosuppression upgrade effectively treated autoimmune myocarditis, which resulted in ventricular function recovery, resolution of arrhythmia, and of troponin release. (Level of Difficulty Advanced.).
AHA, anti-heart autoantibodies; AIDA, anti-intercalated autoantibodies; CMR, cardiac magnetic resonance; EMB, endomyocardial biopsy; HRCT, high-resolution chest computed tomography; LVEF, left ventricle ejection fraction; MCTD, mixed connective tissue disease; MMF, mycophenolate mofetil; MTP, methylprednisolone; SID, systemic immune mediated disease; autoimmune; cardiomyopathy; chronic heart failure
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article