Sudden Cardiac Arrest in a Patient With Mitral Valve Prolapse and LMNA and SCN5A Mutations.
JACC Case Rep
; 3(2): 242-246, 2021 Feb.
Article
em En
| MEDLINE
| ID: mdl-34317510
Bileaflet mitral valve prolapse (Bi-MVP) is associated with increased risk for cardiac arrest. We describe a patient who presented after a cardiac arrest with Bi-MVP and variants in Lamin A/C (LMNA) and the sodium channel alpha-subunit 5a (SCN5A). Genetic variants may be the culprit for arrhythmogenesis in Bi-MVP patients. (Level of Difficulty: Intermediate.).
CADD, Combined Annotation Dependent Depletion; ECG, electrocardiogram; LV, left ventricle; MAD, mitral annular disjunction; MRI, magnetic resonance imaging; MSC, mutation significance cutoff; MVP, mitral valve prolapse; QTc, corrected QT; VF, ventricular fibrillation; genetic disorders; mitral valve; ventricular fibrillation
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article