CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations-Implication for Drug Safety, Dosing, and Individualized Therapy.

Langmia, Immaculate M; Just, Katja S; Yamoune, Sabrina; Brockmöller, Jürgen; Masimirembwa, Collen; Stingl, Julia C

Langmia, Immaculate M; Just, Katja S; Yamoune, Sabrina; Brockmöller, Jürgen; Masimirembwa, Collen; Stingl, Julia C.

Afiliação

Langmia IM; Institute of Clinical Pharmacology, University Hospital of Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Just KS; Institute of Clinical Pharmacology, University Hospital of Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Yamoune S; Institute of Clinical Pharmacology, University Hospital of Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Brockmöller J; Department of Clinical Pharmacology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
Masimirembwa C; African Institute of Biomedical Science and Technology (AiBST), Harare, Zimbabwe.
Stingl JC; Institute of Clinical Pharmacology, University Hospital of Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.

Front Genet ; 12: 692234, 2021.

Article em En | MEDLINE | ID: mdl-34322158

Palavras-chave

adverse drug reaction; cytochrome P450 2B6; drug metabolism; drug safety; genetic polymorphism; personalized medicine; pharmacogenetics; pharmacogenomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article