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A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.
Li, Meiqing; Lu, Danyi; Cheng, Yulian; Wu, Chunlei; Zhang, Jianchao; Shi, Wenli; Ding, Zhihao; Li, Yanyan; Cheng, Binghua; Lin, Xian; Shao, Ximing; Li, Hongchang; Fang, Lijing; Liu, Ke; Su, Wu.
Afiliação
  • Li M; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Lu D; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; Institute of Molecular Rhythm and Metabolism, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
  • Cheng Y; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; Nano Science and Technology Institute, University of Science and Technology of China, Suzhou, 215123, Jiangsu, China.
  • Wu C; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
  • Zhang J; Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
  • Shi W; School of Life and Pharmaceutical Sciences, Hainan University, Haikou, 570228, China; Hainan Key Laboratory for Sustainable Utilization of Tropical Bioresources, College of Tropical Crops, Hainan University, Haikou, 570228, China.
  • Ding Z; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
  • Li Y; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Cheng B; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Lin X; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
  • Shao X; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
  • Li H; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
  • Fang L; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address: lj.fang@siat.ac.cn.
  • Liu K; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address: ke.liu@siat.ac.cn.
  • Su W; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address: wu.su@siat.ac.cn.
Biochem Biophys Res Commun ; 571: 167-173, 2021 09 24.
Article em En | MEDLINE | ID: mdl-34330060
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Inibidores de Proteínas Quinases / Aurora Quinase A / Imidazóis / Antineoplásicos / Nylons Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Inibidores de Proteínas Quinases / Aurora Quinase A / Imidazóis / Antineoplásicos / Nylons Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article