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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Martinelli, Silvia; Anderzhanova, Elmira A; Bajaj, Thomas; Wiechmann, Svenja; Dethloff, Frederik; Weckmann, Katja; Heinz, Daniel E; Ebert, Tim; Hartmann, Jakob; Geiger, Thomas M; Döngi, Michael; Hafner, Kathrin; Pöhlmann, Max L; Jollans, Lee; Philipsen, Alexandra; Schmidt, Susanne V; Schmidt, Ulrike; Maccarrone, Giuseppina; Stein, Valentin; Hausch, Felix; Turck, Christoph W; Schmidt, Mathias V; Gellner, Anne-Kathrin; Kuster, Bernhard; Gassen, Nils C.
Afiliação
  • Martinelli S; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany. silviamartinelli@outlook.de.
  • Anderzhanova EA; Research Group Neurohomeostasis, Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
  • Bajaj T; Department of Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Munich, Germany.
  • Wiechmann S; Research Group Neurohomeostasis, Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
  • Dethloff F; Chair of Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer-Forum 5, Freising, Germany.
  • Weckmann K; German Cancer Consortium (DKTK), Munich, Germany.
  • Heinz DE; German Cancer Center (DKFZ), Heidelberg, Germany.
  • Ebert T; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Hartmann J; Metabolomics Core Facility, Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Geiger TM; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Döngi M; Research Group Neurohomeostasis, Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
  • Hafner K; Department of Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Munich, Germany.
  • Pöhlmann ML; Research Group Neurohomeostasis, Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
  • Jollans L; Department of Psychiatry, Harvard Medical School and McLean Hospital, Belmont, MA, USA.
  • Philipsen A; Institute for Organic Chemistry and Biochemistry, Technische Universität Darmstadt, Darmstadt, Germany.
  • Schmidt SV; Institut für Physiologie II, University of Bonn, Bonn, Germany.
  • Schmidt U; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Maccarrone G; Research Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich, Germany.
  • Stein V; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Hausch F; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
  • Turck CW; Institute of Innate Immunity, University of Bonn, Bonn, Germany.
  • Schmidt MV; Research Group Molecular and Clinical Psychotraumatology, Department of Psychiatry and Psychotherapy, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
  • Gellner AK; Research Group Traumatic Stress & Neurodegeneration & PTSD Treatment Unit, Department of Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), Göttingen, Germany.
  • Kuster B; Department of Psychiatry and Neuropsychology, Maastricht University Medical Centre, School for Mental Health and Neuroscience, Maastricht, The Netherlands.
  • Gassen NC; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
Nat Commun ; 12(1): 4643, 2021 07 30.
Article em En | MEDLINE | ID: mdl-34330919
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Dexametasona / Fator Neurotrófico Derivado do Encéfalo / Metaloproteinase 9 da Matriz Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Dexametasona / Fator Neurotrófico Derivado do Encéfalo / Metaloproteinase 9 da Matriz Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article