Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs.

Christen, Matthias; Högler, Sandra; Kleiter, Miriam; Leschnik, Michael; Weber, Corinna; Thaller, Denise; Jagannathan, Vidhya; Leeb, Tosso

Christen, Matthias; Högler, Sandra; Kleiter, Miriam; Leschnik, Michael; Weber, Corinna; Thaller, Denise; Jagannathan, Vidhya; Leeb, Tosso.

Afiliação

Christen M; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Högler S; Unit of Laboratory Animal Pathology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Kleiter M; Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
Leschnik M; Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
Weber C; Laboklin GmbH & Co. KG, Laboratory for Clinical Diagnostics, Bad Kissingen, Germany.
Thaller D; Institute of Pathology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Jagannathan V; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Leeb T; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

PLoS Genet ; 17(8): e1009716, 2021 08.

Article em En | MEDLINE | ID: mdl-34339417

Assuntos

Ataxia Cerebelar/genética; Selenoproteína P/genética; Selenoproteína P/metabolismo; Animais; Atrofia/fisiopatologia; Sistema Nervoso Central/fisiologia; Ataxia Cerebelar/metabolismo; Doenças do Cão/genética; Cães; Feminino; Ligação Genética/genética; Genoma/genética; Genótipo; Homozigoto; Masculino; Fenótipo; Sequenciamento Completo do Genoma/métodos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ataxia Cerebelar / Selenoproteína P Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google