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Cripto favors chondrocyte hypertrophy via TGF-ß SMAD1/5 signaling during development of osteoarthritis.
Garcia de Vinuesa, Amaya; Sanchez-Duffhues, Gonzalo; Blaney-Davidson, Esmeralda; van Caam, Arjan; Lodder, Kirsten; Ramos, Yolande; Kloppenburg, Margreet; Meulenbelt, Ingrid; van der Kraan, Peter; Goumans, Marie-José; Ten Dijke, Peter.
Afiliação
  • Garcia de Vinuesa A; Department of Cell and Chemical Biology, Leiden University Medical Center, Oncode Institute, Leiden, The Netherlands.
  • Sanchez-Duffhues G; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Blaney-Davidson E; Experimental Rheumatology & Advanced Therapeutics, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • van Caam A; Experimental Rheumatology & Advanced Therapeutics, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Lodder K; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Ramos Y; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
  • Kloppenburg M; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
  • Meulenbelt I; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
  • van der Kraan P; Experimental Rheumatology & Advanced Therapeutics, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Goumans MJ; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Ten Dijke P; Department of Cell and Chemical Biology, Leiden University Medical Center, Oncode Institute, Leiden, The Netherlands.
J Pathol ; 255(3): 330-342, 2021 11.
Article em En | MEDLINE | ID: mdl-34357595

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Fator de Crescimento Transformador beta / Condrócitos / Peptídeos e Proteínas de Sinalização Intercelular / Proteínas Smad / Proteínas Ligadas por GPI / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Fator de Crescimento Transformador beta / Condrócitos / Peptídeos e Proteínas de Sinalização Intercelular / Proteínas Smad / Proteínas Ligadas por GPI / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article