Curcumin attenuates prostatic hyperplasia caused by inflammation <i>via</i> up-regulation of bone morphogenetic protein and activin membrane-bound inhibitor.

Liu, Yuhang; Wang, Zhaohui; Gan, Yu; Chen, Xiang; Zhang, Bo; Chen, Zhi; Liu, Peihuan; Li, Bingsheng; Ru, Feng; He, Yao

Curcumin attenuates prostatic hyperplasia caused by inflammation via up-regulation of bone morphogenetic protein and activin membrane-bound inhibitor.

Liu, Yuhang; Wang, Zhaohui; Gan, Yu; Chen, Xiang; Zhang, Bo; Chen, Zhi; Liu, Peihuan; Li, Bingsheng; Ru, Feng; He, Yao.

Afiliação

Liu Y; Department of Urology, Hunan Children's Hospital, Changsha, Hunan, China.
Wang Z; Department of Urology, Hunan Children's Hospital, Changsha, Hunan, China.
Gan Y; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chen X; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhang B; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chen Z; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Liu P; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Li B; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ru F; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
He Y; Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Pharm Biol ; 59(1): 1026-1035, 2021 Dec.

Article em En | MEDLINE | ID: mdl-34357837

Assuntos

Proteínas Morfogenéticas Ósseas/metabolismo; Curcumina/farmacologia; Proteínas de Membrana/metabolismo; Hiperplasia Prostática/tratamento farmacológico; Animais; Caderinas/metabolismo; Linhagem Celular; Citocinas/efeitos dos fármacos; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Humanos; Inflamação/metabolismo; Lipopolissacarídeos/farmacologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Modelos Animais; Próstata/efeitos dos fármacos; Próstata/patologia; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/metabolismo; Fator de Crescimento Transformador beta1/metabolismo; Regulação para Cima; Vimentina/metabolismo

Palavras-chave

Benign prostatic hyperplasia; Toll-like receptor 4; epithelial-mesenchymal transition; lipopolysaccharide; tumour necrosis factor-α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hiperplasia Prostática / Proteínas Morfogenéticas Ósseas / Curcumina / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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